body {
            font-family: 'Georgia', 'Times New Roman', sans-serif;
            line-height: 1.6;
            margin: 0;
            padding: 0;
            background-color: #f8f8f8;
            color: #333;
        }
        
        .container {
            max-width: 800px;
            margin: 0 auto;
            padding: 20px;
            background-color: white;
            box-shadow: 0 0 10px rgba(0,0,0,0.1);
        }
        
        .breadcrumb {
            font-size: 0.9em;
            color: #666;
            margin-bottom: 20px;
        }
        
        .breadcrumb a {
            color: #d32f2f;
            text-decoration: none;
        }
        
        .breadcrumb a:hover {
            text-decoration: underline;
        }
        
        header {
            text-align: center;
            border-bottom: 3px solid #d32f2f;
            padding-bottom: 20px;
            margin-bottom: 30px;
        }
        
        h1 {
            color: #d32f2f;
            font-size: 2.2em;
            margin-bottom: 10px;
            font-weight: normal;
        }
        
        .article-meta {
            color: #666;
            font-style: italic;
            font-size: 0.9em;
            margin-bottom: 20px;
        }
        
        .article-content {
            text-align: justify;
            margin-bottom: 30px;
        }
        
        .article-content p {
            margin-bottom: 18px;
        }
        
        .microscopy-section {
            margin: 40px 0;
            padding: 20px;
            background-color: #fafafa;
            border-radius: 5px;
        }
        
        .microscopy-section h2 {
            color: #d32f2f;
            font-size: 1.3em;
            margin-bottom: 15px;
        }
        
        .image-container {
            text-align: center;
            margin: 30px 0;
        }
        
        .image-placeholder {
            width: 350px;
            height: 250px;
            background-color: #e0e0e0;
            border: 2px dashed #999;
            display: inline-block;
            line-height: 250px;
            color: #666;
            font-style: italic;
            max-width: 100%;
        }
        
        .hover-effect {
            background-color: #f0f0f0;
            padding: 15px;
            border-radius: 5px;
            margin: 20px 0;
            border: 1px solid #ddd;
            cursor: pointer;
            transition: background-color 0.3s ease;
        }
        
        .hover-effect:hover {
            background-color: #e8f5e8;
        }
        
        .navigation {
            background-color: #f0f0f0;
            padding: 20px;
            border-radius: 5px;
            margin: 30px 0;
            text-align: center;
        }
        
        .nav-button {
            display: inline-block;
            background-color: #d32f2f;
            color: white;
            padding: 10px 20px;
            margin: 0 10px;
            text-decoration: none;
            border-radius: 3px;
            font-size: 0.9em;
        }
        
        .nav-button:hover {
            background-color: #b71c1c;
            text-decoration: none;
        }
        
        .footer {
            text-align: center;
            margin-top: 40px;
            padding-top: 20px;
            border-top: 1px solid #eee;
            color: #666;
            font-size: 0.9em;
        }
        
        a {
            color: #d32f2f;
            text-decoration: none;
        }
        
        a:hover {
            text-decoration: underline;
        }