| Crew-Nr | Flight | Name | Call | comment |
| 1 | TM-31 | William Shepherd | KD5GSL | Expedition commander |
| 1 | TM-31 | Sergei Krikalev | U5MIR | flight engineer |
| 2 | STS-102 | Yuri Usachev | UA9AD/R3MIR | |
| 2 | STS-102 | Susan Helms | KC7NHZ | |
| 3 | STS-105 | Culbertson | KD5OPQ | commander |
| 3 | STS-105 | Mikhail Turin | ||
| 3 | STS-105 | Vladimir Dezhurov | ||
| 4 | STS-106 | Dan Bursch | KD5PNU | Flight Engineer |
| 4 | STS-106 | Carl Walz | KC5TIE | Flight Engineer |
| 4 | STS-111 | Yuri Onufrienko | RK3DUO | Flight Engineer |
| 4 | ? | Dennis Tito | KG6FZX | Tourist |
| 4 | TM-24 | Roberto Vittori | IZ6ERU | flight engineer |
| 5 | STS-111 | Valery Korzun | RZ3FK | Flight commander |
| 5 | STS-111 | Sergei Yevgenyevich Treschev | RZ3FU | light engineer |
| 5 | TM-24 | Peggy Whitson | KC5ZTD | flight engineer |
| prepared | TMA-1 | Jeramy Boot | G4NJH | flight engineer |
| 6 | STS-113 | Kenneth Bowersox | KD5JBP | flight engineer |
| 6 | STS-113 | Donald Pettit | KD5MDT | flight engineer |
| 7 | TMA-2 | Yuri Malenchenko | RK3DUP | expedition commander |
| 7 | TMA-2 | Ed Lu | KC5WKJ | flight engineer |
| 8 | STS-116 | Michael Foal | KB5UAC | expedition commander |
| 8 | STS-116 | William McArthuer | KC5ACR | flight engineer |